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In addition, surface transporters of epithelial cells, such as glucose transporter GLUT2 and amino acid transporter SGLT1, can specifically transport nutrients, further enhancing the selectivity of permeability

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However, 30%-40% of tumors treated with tamoxifen develop resistance

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On the one hand, the redundancy and genetic interaction of these core transcription factors reveal their dose-dependent regulatory mechanism and the core role in biofilm formation, providing a genetic basis for developing antifungal strategies targeting this network (Glazier et al., 2017)